Terpenoid-type quinones for treatment of diabetes
AssigneeShaman Pharmaceuticals, Inc.
InventorsRosa P. Ubillas, Jolad D. Shivanand, Christopher D. Mendez, Diana M. Fort, Joseph L. Evans, Jian Luo
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Abstract
Novel terpenoid-type quinones which can be obtained from Pycnanthus spp., processes for obtaining the novel terpenoid-type quinones and methods for their use as hypoglycemic agents, for example, in the treatment of diabetes are described. In a preferred embodiment, the novel terpenoid-type quinones are obtained from the leaves and stems of Pycnanthus angolensis. As agents for the treatment of diabetes, the novel terpenoid quinones are useful for treating insulin-dependent (type I) and/or non-insulin-dependent (type II) diabetes.
Claims25
A compound having the structure of compound 3:
- ##STR13## or the structure of compound 4:
- ##STR14## or pharmaceutically acceptable salts thereof.
A compound having the following structure:
- ##STR15## or pharmaceutically acceptable salts thereof.
A compound having the following structure:
- ##STR16## or pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.