Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones
AssigneesSumitomo Seika Chemicals Co., Ltd., Sumitomo Chemical Company, Limited
InventorsHirokazu Kagano, Hiroshi Goda, Shigeki Sakaue
Life of this patent
Estimating the term…
Abstract
A method for producing an alkylthiobenzamide by carrying out a reaction of a halobenzamide with an alkanethiol in the presence of a base in a heterogeneous solvent; a method for producing an alkylsulfinylbenzamide by carrying out a reaction of an alkylthiobenzamide with a halogen in a heterogeneous solvent; a method for producing an alkylsulfinylbenzamide by carrying out a reaction of a halobenzamide with an alkanethiol in the presence of a base in a heterogeneous solvent and a subsequent reaction with a halogen; and a method for producing a 1,2-benzisothiazol-3-one by carrying out a reaction of a 2-(alkylthio)benzamide with a halogenating agent.
Claims5
A method for producing an alkylthiobenzamide represented by the general formula (III), comprising carrying out a reaction of a halobenzamide represented by the following general formula (I):
- ##STR17## wherein X represents Cl or Br, and R.sup.1 represents a hydrogen atom, or an alkyl group having 1 to 4 carbon atoms, an aryl group, or an aralkyl group,
- with an alkanethiol represented by the following general formula (II):
- R.sup.2 SH (II)
- wherein R.sup.2 represents an alkyl group having 1 to 4 carbon atoms, in the presence of a base and a phase-transfer catalyst in a heterogeneous solvent,
- to give an alkylthiobenzamide represented by the following general formula (III):
- ##STR18## wherein R.sup.1 and R.sup.2 are defined as above.
Dependencies are inferred from the claim text.