Methods of increasing macrophage function
AssigneeEli Lilly and Company
InventorSteven H. Zuckerman
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Abstract
A method of increasing macrophage function comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof. Also encompassed by the invention is a method of treating immunocompromissed individuals comprising administering a compound of formula 1.
Claims8
A method of increasing macrophage function so as to augment a humans defense comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR5## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR6## wherein Ar is optionally substituted phenyl;
- R.sup.2 is selected from the group consisting of pyrrolidine, hexamethylenemino, and piperidino;
- or a pharmaceutically acceptable salt of solvate thereof.
A method of treating an immunocompromised human comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR8## wherein R.sup.1 and R.sup.1 are independently hydrogen, --CH.sub.3, ##STR9## wherein Ar is optionally substituted phenyl;
- R.sup.2 is selected from the group consisting of pyrrolidine, hexamethylenemino, and piperidino;
- or a pharmaceutically acceptable salt of solvate thereof.
Dependencies are inferred from the claim text.