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US 5,672,356 AGranted
Bioadhesive pharmaceutical composition for the controlled release of active principles
AssigneeAdir et Compagnie
InventorsIsabelle Rault, Gerald Pichon, Alain Cuine
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Abstract
Bioadhesive pharmaceutical composition for the controlled release of active principles locally across the buccal cavity or systemically across a mucous membrane, wherein it is composed of an active principle, a compound (A), a compound (B) and excipients as defined in the description.
Claims4
A bioadhesive pharmaceutical composition for the controlled release of an active principle locally in the buccal cavity or systemically across a mucous membrane, which comprises:
- an active principle,
- a compound (A) selected from the group consisting of a copolymer formed by the copolymerization of methyl vinyl ether and maleic anhydride, a derivative thereof, and mixtures thereof,
- a compound (B) which is acetylated maize starch,
- and therapeutically acceptable excipients,
- wherein the amount of (A) is between 5 and 85% of the total mass of the composition and
- wherein the amount of (B) is between 5 and 85% of the total mass of the composition,
- said composition being wet granulated and compressed into a tablet.
4 more elements
Dependencies are inferred from the claim text.