Tumor necrosis factor antagonists and their use
AssigneeGenentech, Inc.
InventorsBharat B. Aggarwal, Michael A. Palladino, Mohamed R. Shalaby
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Abstract
Tumor necrosis factor antagonists are administered in therapeutically effective doses to suppress inflammatory immune-potentiated events. The antagonists of this invention typically are selected from among several classes but preferably are neutralizing antibodies directed against tumor necrosis factor. The antagonists are useful in suppressing transplantation immunity and in the treatment of autoimmune diseases.
Claims7
A method for treatment of a graft versus host reaction which comprises administering to a patient a therapeutically effective dose of a tumor necrosis factor-alpha ("TNF-.alpha.") antagonist.
Dependencies are inferred from the claim text.