Back to results
US 5,672,343 AGranted
N- 3 deletion mutants of the long form of CSF-1
AssigneeChiron Corporation
InventorsMartha B. Ladner, Janelle A. Noble, George A. Martin, Ernest S. Kawasaki, Mazie Yee Coyne, Robert F. Halenbeck, Kirston E. Koths
Life of this patent
Estimating the term…
Abstract
New forms of CSF-1 are provided which relate to N-terminal truncations. Specifically, N-.gradient.3 terminal truncations of the long form of CSF-1 have been found to be particularly advantageous. These forms may have a C-terminal truncation at a variety of different amino acids beyond position 150.
Claims15
A CSF-1 polypeptide consisting of amino acids 4 to 522 of the sequence shown in SEQ ID NO:
- 2 or a carboxy truncated polypeptide thereof, wherein the carboxy truncated polypeptide contains at least amino acids 4-149 of SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.