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US 5,672,213 AGranted
Liquid enzyme compositions containing aromatic acid derivatives
AssigneeAlcon Laboratories, Inc.
InventorsBahram Asgharian, Ronald P. Quintana, Bor-Shyue Hong
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Abstract
Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
Claims10
A liquid protease composition for cleaning contact lenses comprising an enzyme in an amount effective to clean the lens;
- 0.01-5.0% w/v of an aromatic acid derivative;
- 30-70% w/v of at least one polyol selected from the group consisting of:
- propylene glycol, ethylene glycol, sorbitol, manitol, and polymeric polyols having a molecular weight ranging from 200-1000 daltons;
- and water.
1 more element
A liquid protease composition for cleaning contact lenses comprising an enzyme in an amount effective to clean the lens;
- 30-70% w/v of at least one polyol;
- water;
- and 0.01-5.0% w/v of an aromatic acid derivative according to formulas (I), (II) or (III):
- ##STR3## wherein:
- R is H, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 hydroxyalkyl or hydroxy;
- n is 0 to 3;
- n' is 1-3;
- or suitable salts of the acids.
5 more elements
Dependencies are inferred from the claim text.