Method for making a substituted benzene compound
AssigneeRohm and Haas Company
InventorsLori Ann Spangler, Damian Gerard Weaver
Life of this patent
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Abstract
A method for making a substituted benzene compound includes reacting a 2-substituted benzenesulfonate or the 2-substituted benzenesulfonate further substituted in the 3, 4 or 5-position with a lithium compound to form an intermediate; and reacting the intermediate with an electrophile to form a 2,6-disubstituted benzenesulfonate or a 2,6-disubstituted benzenesulfonate further substituted in the 3, 4 or 5-position.
Claims13
A method for making a substituted benzene compound which comprises reacting a 2-substituted benzenesulfonate or a 2-substituted benzenesulfonate, further substituted in the 3, 4 or 5-position, with a lithium compound to form an intermediate compound;
- and reacting said intermediate compound with an electrophile to form a 2,6-disubstituted benzenesulfonate or a 2,6-disubstituted benzenesulfonate further substituted in the 3, 4 or 5-position, said 2-substituted benzenesulfonate or said 2-substituted benzenesulfonate further substituted in the 3, 4 or 5-position being a compound of the formula ##STR8## wherein R.sub.1 is alkyl, cycloalkyl or phenyl;
- X is any group that is not reactive with the lithium compound under the reaction conditions used;
- and
- Y is any group in the 3, 4 or 5-position that is not reactive with the lithium compound under the reaction conditions used.
Dependencies are inferred from the claim text.