Collagen-like polypeptides and biopolymers and nucleic acids encoding same
AssigneeEastman Kodak Company
InventorsShane Crawford Weber, John Alan McElver
Life of this patent
Estimating the term…
Abstract
Synthetic biopolymers can be prepared using recombinant DNA technology or chemical synthetic methods which have properties similar to naturally occuring gelatin or collagen. These materials comprise one or more polypeptides having the peptide sequence represented by the formulae I: {(Gly Pro Gln)(Gly Pro Glu).sub.4 !.sub.2 }.sub.n II: Gly Pro Glu{(Gly Pro Gln)(Gly Pro Glu).sub.4 !.sub.2 }.sub.n III: Gly Pro Xaa.sub.1 Gly Leu Xaa.sub.2 Gly Pro Arg Gly Pro Pro Gly Ala Set Gly Ala Pro Gly Pro Glu Gly Phe Gln Gly wherein Xaa.sub.1 and Xaa.sub.2 are independently the amino acids identified as Met, Ile, His, Lys, Asn, Tyr or Gln, and n is 1 to 25.
Claims18
A polypeptide comprising the peptide sequence represented by the formula:
- I:
- {(Gly Pro Gln)(Gly Pro Glu).sub.4 !.sub.2 }.sub.n
- II:
- Gly Pro Glu{(Gly Pro Gln)(Gly Pro Glu).sub.4 !.sub.2 }.sub.n
- or III:
- Gly Pro Xaa.sub.1 Gly Leu Xaa.sub.2 Gly Pro Arg Gly Pro Pro Gly Ala Ser Gly Ala Pro Gly Pro Glu Gly Phe Gln
- wherein
- Xaa.sub.1 and Xaa.sub.2 are independently the amino acids identified as Met, Ile, His, Lys, Asn, Tyr or Gln, and n is 1 to 25.
A recombinant polypeptide having at least one occurrence of a peptide sequence represented by the formula:
- I:
- {(Gly Pro Gln)(Gly Pro Glu).sub.4 !.sub.2 }.sub.n
- II:
- Gly Pro Glu{(Gly Pro Gln)(Gly Pro Glu).sub.4 !.sub.2 }.sub.n
- or III:
- Gly Pro Xaa.sub.1 Gly Leu Xaa.sub.2 Gly Pro Arg Gly Pro Pro Gly Ala Ser Gly Ala Pro Gly Pro Glu Gly Phe Gln Gly
- wherein
- Xaa.sub.1 and Xaa.sub.2 are independently the amino acids identified as Met, Ile, His, Lys, Asn, Tyr or Gln, and n is 1 to 25.
A recombinant polypeptide having a peptizing function for controlling the growth of silver halide crystals, said polypeptide also having at least one occurrence of a peptide sequence represented by the formula:
- I:
- {(Gly Pro Gln)(Gly Pro Glu).sub.4 !.sub.2 }.sub.n
- II:
- Gly Pro Glu{(Gly Pro Gln)(Gly Pro Glu).sub.4 !.sub.2 }.sub.n
- or III:
- Gly Pro Xaa.sub.1 Gly Leu Xaa.sub.2 Gly Pro Arg Gly Pro Pro Gly Ala Ser Gly Ala Pro Gly Pro Glu Gly Phe Gln Gly
- wherein
- Xaa.sub.1 and Xaa.sub.2 are independently the amino acids identified as Met, Ile, His, Lys, Asn, Tyr or Gln, and n is 1 to 25.
A process for staining a polypeptide comprising a peptide sequence represented by the formula:
- I:
- {(Gly Pro Gln)(Gly Pro Glu).sub.4 !.sub.2 }.sub.n
- II:
- Gly Pro Glu{(Gly Pro Gln)(Gly Pro Glu).sub.4 !.sub.2 }.sub.n
- or III:
- Gly Pro Xaa.sub.1 Gly Leu Xaa.sub.2 Gly Pro Arg Gly Pro Pro Gly Ala Ser Gly Ala Pro Gly Pro Glu Gly Phe Gln Gly
- wherein
- Xaa.sub.1 and Xaa.sub.2 are independently the amino acids identified as Met, Ile, His, Lys, Asn, Tyr or Gln, and n is 1 to 25 comprising:
- contacting said polypeptide with a cationic carbocyanine dye.
Dependencies are inferred from the claim text.