Synthesis of tyrosine-derived diphenol monomers
AssigneeRutgers, The State University
InventorsJoachim B. Kohn, Stephen J. Brocchini, Arthur L. Schwartz
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Abstract
A method for preparing diphenol compounds, which method includes the steps of coupling a hydroxyphenyl carboxylic acid with a L-tyrosine ester in a water-miscible organic reaction solvent containing a carbodiimide capable of forming a water-soluble urea by-product, thereby forming a diphenol reaction product; and combining the reaction mixture with an amount of water effective to precipitate the diphenol as a water-immiscible organic phase, so that a water-immiscible organic phase is formed containing the diphenol reaction product. New diphenol monomers and polymers polymerized therefrom are also disclosed.
Claims7
An L-tyrosine derived diphenol compound having the structure:
- ##STR8## wherein R.sub.1 is selected from the group consisting of --CH.dbd.CH--, --CH.sub.2 --, and (--CH.sub.2 --).sub.n, in which n is zero, one, or an integer from three to eight;
- and R.sub.2 is selected from the group consisting of straight and branched and alkyl alkylaryl groups containing up to 18 carbon atoms.
Dependencies are inferred from the claim text.