8-substituted styryl xanthine derivatives
AssigneeKyowa Hakko Kogyo Co., Ltd.
InventorsFumio Suzuki, Junichi Shimada, Nobuaki Koike, Hiroshi Kase, Joji Nakamura, Shizuo Shiozaki, Hiromi Nonaka
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AssigneeKyowa Hakko Kogyo Co., Ltd.
InventorsFumio Suzuki, Junichi Shimada, Nobuaki Koike, Hiroshi Kase, Joji Nakamura, Shizuo Shiozaki, Hiromi Nonaka
Estimating the term…
Disclosed are xanthine derivatives represented by the following Formula (I): ##STR1## in which R.sup.1, R.sup.2, and R.sup.3 independently represent hydrogen or lower alkyl; Q.sup.1, Q.sup.2, and Q.sup.3 independently represent hydrogen, lower alkyl, lower alkoxy, or halogen; and X represents --COR.sup.4 (in which R.sup.4 represents hydrogen, hydroxy, lower alkyl, or lower alkoxy) or --SO.sub.2 R.sub.5 {in which R.sup.5 represents hydroxy, lower alkoxy, trifluoromethyl, ##STR2## in which R.sup.6 and R.sup.7 independently represent hydrogen, hydroxy-substituted or unsubstituted lower alkyl, aryl, or ##STR3## (in which m represents an integer of 1 to 3; and R.sup.8 and R.sup.9 independently represent hydrogen or lower alkyl), or ##STR4## (in which Y represents a single bond, oxygen, or N--R.sup.10 in which R.sup.10 represents hydrogen or lower alkyl; and n1 and n2 independently represent an integer of 1 to 3)}, and pharmaceutically acceptable salts thereof.
A xanthine derivative represented by the following Formula (I):
Dependencies are inferred from the claim text.