Porous particle aggregate and method therefor
AssigneeFuisz Technologies Ltd.
InventorRoy L. Whistler
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Abstract
A porous aggregate having a high intraaggregate reticular volume for releasable containment of functional substances is described. The porous aggregates comprise discrete particles, preferably starch granules, bound together at least at their points of contact in the aggregates. The surfaces of the discrete particles cooperate to define an intraaggregate reticulate volume. The porous aggregate composition of this invention finds use as a high capacity carrier of functional substances for a wide variety of applications, in which the functional substance is released from the aggregate composition under the influence of mechanical compression/disintegration, by degradation or dissolution of the binder and/or particulate components, or by diffusion from the porous surface.
Claims22
A method for preparing porous aggregates of discrete particles having an average particle size of about 1 to about 100 microns in their largest dimension, said aggregated particles bound together in said porous aggregate with a binder not endogenous to the discrete particles at least at their points of contact in said aggregate, the surfaces of said aggregated particles cooperating to define an intraaggregate reticular volume adapted for releasable containment of functional substances, said method comprising the steps of forming a suspension of said particles in a solution of the binder and spray drying said suspension.
A composition comprising an aggregate of discrete particles, said particles having an average particle size of about 1 to about 100 microns in their largest dimension, said particles bound together with a binder not endogenous to the particles at least at their points of contact in said aggregate, the surfaces of said aggregated particles cooperating to define an intraaggregate reticular volume adapted for releasable containment of functional substances.
Dependencies are inferred from the claim text.