Antibody to human interleukin-6 receptor
OwnerTadamitsu Kishimotoinventor
Life of this patent
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Abstract
Antibodies, polyclonal and monoclonal, which are capable of specifically binding to a human interleukin-6 receptor. Also included are monoclonal antibodies which competitively and non-competitively inhibit human interleukin-6, and a method of producing hybridomas of the said monoclonal antibodies capable of specifically binding to a human interleukin-6 receptor.
Claims13
An isolated antibody to human interleukin-6 receptor, wherein said antibody specifically binds to said human interleukin-6 receptor.
A hybridoma capable of producing a monoclonal antibody to human interleukin-6 receptor, wherein said monoclonal antibody can specifically bind to human interleukin-6 receptor.
A process for the production of a monoclonal antibody to human interleukin-6 receptor, wherein said monoclonal antibody is capable of specifically binding human interleukin-6 receptor, comprising the steps of
- 1) culturing hybridoma cells producing said monoclonal antibody;
- and
- 2) recovering the supernatant from said culturing step.
A process for the preparation of a polyclonal antibody directed against human interleukin-6 receptor, comprising the steps of
- 1) immunizing an animal with a peptide having the amino acid sequence KTS MHP PYS LGQ LVP;
- and
- 2) recovering said polyclonal antibody from said immunized animal.
Dependencies are inferred from the claim text.