Nucleotide-containing sorbent for affinity chromatography
AssigneeMerck Patent GmbH
InventorsEgbert Muller, Jurgen Hemberger, Michael Morr
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AssigneeMerck Patent GmbH
InventorsEgbert Muller, Jurgen Hemberger, Michael Morr
Estimating the term…
The invention relates to sorbents for for sic! affinity chromatography which are based on hydroxyl-containing base supports on whose surfaces polymers are covalently bonded, characterized in that a) the base support contains aliphatic hydroxyl groups, b) the covalently bonded polymers are bound to the base support by a terminal monomer unit, c) the polymers contain monomer units of the formula II d) the monomer units are linked linearly, ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 independently of one another are H or CH.sub.3, R.sup.4 is H, C.sub.1 -C.sub.5 -alkyl or C.sub.6 -C.sub.12 -aryl, n is an integer between 1 and 5 and one of the radicals X is OH and the other radical X is a nucleoside-containing radical, and to their preparation and use, especially for affinity chromatography.
A separation material for affinity chromatography comprising a hydroxyl-containing base support on the surface of which polymers are covalently bonded, wherein
Dependencies are inferred from the claim text.