Polynucleotides encoding mammaglobin, a mammary-specific breast cancer protein
AssigneeWashington University
InventorsMark A. Watson, Timothy P. Fleming
Life of this patent
Estimating the term…
Abstract
A purified and isolated DNA sequence and the encoded mammary-specific protein, mammaglobin, are disclosed. Also disclosed are methods for the detecting breast cancer based upon the overexpression and secretion of mammaglobin by breast cancer cells. The methods detect and/or quantitate the presence of mammaglobin or the mRNA encoding mammaglobin.
Claims15
An isolated and purified polynucleotide encoding mammaglobin, or a fragment of said polynucleotide that specifically hybridizes to the complement of SEQ ID NO:1.
An isolated and purified polynucleotide that specifically hybridizes to SEQ ID NO:1, or the complement of said polynucleotide.
A kit for detection of the presence of breast neoplasia cells in a sample comprising,
- an isolated and purified polynucleotide encoding mammaglobin, or the complement of said polynucleotide, or a fragment of said polynucleotide that specifically hybridizes to the complement of SEQ ID NO:1, packaged in a container.
A kit for detection of the presence of breast neoplasia cells in a sample comprising,
- an isolated and purified polynucleotide that specifically hybridizes to SEQ ID NO:1, or specifically hybridizes to the complement of SEQ ID NO:1, packaged in a container.
Dependencies are inferred from the claim text.