Use of selective ligands for treatment of disease states responsive to steroid or steroid-like retinoids
AssigneeThe Salk Institute for Biological Studies
InventorsRonald M. Evans, Richard A. Heyman, Christina S. Berger, Robert B. Stein
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Abstract
In accordance with the present invention, there is provided a method for the treatment of subjects afflicted with steroid or steroid-like hormone-responsive disease states. The invention method comprises administering to the subject an effective amount of a ligand which selectively interacts with the receptor subtype associated with the steroid or steroid-like hormone-responsive disease state, wherein said ligand interacts with said receptor subtype to a significantly greater extent than with other subtypes of the same receptor class.
Claims5
A method for the treatment of a retinoid-responsive disease state in a subject, said method comprising administering to said subject an effective amount of a ligand which selectively interacts with the retinoid subtype associated with said retinoid-responsive disease state, to a significantly greater extent than with other retinoid subtypes.
Dependencies are inferred from the claim text.