1-azabicyclopheptane derivatives
AssigneeAmerican Home Products Corporation
InventorsAnnmarie L. Sabb, Reinhardt P. Stein
Life of this patent
Estimating the term…
Abstract
The compounds of the formula: ##STR1## where R is H, alkyl, haloalkyl, cycloalkyl, alkenyl or alkynyl; Y is oxygen, sulfur or NR.sub.2 where R.sub.2 is H or alkyl; or a pharmaceutically acceptable salt thereof, are useful centrally active muscarinic agents.
Claims3
A method for alleviating the symptoms of neurological illness attending acetylcholine deficiency which comprises administering to a patient in need thereof, parenterally or orally, (-)-(exo)-methylcarbamic acid 1-aza-bicyclo[2.2.1]hept-3-yl ester, or a pharmaceutically acceptable salt thereof.
A method of alleviating the symptoms of memory loss attending senility which comprises administering to a patient in need thereof, parenterally or orally, (-)-(exo)-methylcarbamic acid 1-aza-bicyclo[2.2.1]hept-3-yl ester, or a pharmaceutically acceptable salt thereof.
A method for alleviating the neurological symptoms attending Parkinson's disease, Downe's Syndrome or senile pugilistica, which comprises administering to a patient in need thereof, parenterally or orally, (-)-(exo)-methylcarbamic acid 1-aza-bicyclo [2.2.1]hept-3-yl ester, or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.