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US 5,668,138 AGranted
Phenoyalkylpiperazine derivatives
AssigneeAdir et Compagnie
InventorsGenevieve Baziard-Mouysset, Sallouma Younes, Youssef Labssita, Marc Payard, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
Life of this patent
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Abstract
A compound selected from those of formula (I): ##STR1## where RA, RB, RC, RD, A, n, X, Y and Ar are defined in the description, and a medicinal product comprising the same for treating a mammal afflicted with a disease associated with sigma receptors.
Claims4
A compound selected from those of formula (I):
- ##STR17## in which Ar represents phenyl, naphthyl, but Ar is not trisubstituted phenyl when RB is methyl, substituted phenyl or substituted naphthyl,
- n represents 1,
- RB represents alkyl, A represents a single bond and RA and RC, which are identical or different, represent, independently of one another, hydrogen or a group chosen from halogen, alkyl, alkyl substituted by one or a number of halogens, and alkoxy,
- it being understood that, except when otherwise mentioned,
- the terms "alkyl" and "alkoxy" denote linear or branched saturated groups having 1 to 6 carbon atoms inclusive,
- the term "substituted" concerning the phenyl and naphthyl substituents means that the latter can be substituted by one to three groups chosen from hydroxyl, alkyl, alkyl substituted by one or a number of halogens, alkoxy and halogen,
- an optical isomer thereof in the pure form or in the form of a mixture, and an addition salt thereof with a pharmaceutically-acceptable acid or base.
4 more elements
Dependencies are inferred from the claim text.