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AssigneeG. D. Searle & Co.
InventorsPaul Dale Klimstra, Barbara Roniker, Edward Allen Swabb
Estimating the term…
The present invention provides a method for preventing or reducing a photosensitivity and/or phototoxicity reaction which may be caused by a once-per-day dose of a medication which causes a photosensitivity and/or phototoxicity reaction in a patient comprising administering the prescribed or suggested dose of the medication to the patient during the evening or early morning hours. The present invention also provides an article of manufacture comprising: (1) a packaging material, and (2) a once-a-day dose medication which causes a photosensitivity and/or a phototoxicity reaction in a patient contained within said packaging material, wherein such a reaction is prevented or reduced by administering the medication to the patient during the evening or early morning hours, and wherein said packaging material comprises a label which indicates that such a reaction is prevented or reduced by administering the medication to the patient during the evening or early morning hours, and/or that such medication is to be administered during the evening or early morning hours, and/or wherein the packaging material is arranged in a manner which releases the medication to the patient during the evening or early morning hours.
A method for treating an infection in a patient in a manner which prevents or reduces a photosensitivity and/or phototoxicity reaction which method comprises orally administering to said patient a once-a-day dose of about 25 mg to about 700 mg of lomefloxacin hydrochloride between the hours of about 4:00 p.m. and about 4:00 a.m.
A method for preventing or reducing a photosensitivity and/or phototoxicity reaction caused by a once-a-day dose of lomefloxacin hydrochloride in a patient, comprising administering said lomefloxacin hydrochloride to said patient between the hours of about 4:00 p.m. and about 4:00 a.m.
In a method for administering a therapeutically effective amount of a once-a-day dose of lomefloxacin hydrochloride, which lomefloxacin hydrochloride in such a once-a-day therapeutic amount achieves a concentration in the blood which causes a photosensitivity and/or phototoxicity reaction in the patient to whom the lomefloxacin hydrochloride is administered, an improvement in the method comprising administering the lomefloxacin hydrochloride to the patient at a time sufficient for the blood level of said lomefloxacin hydrochloride to be at a concentration which is less than a concentration which produces a photosensitivity and/or phototoxicity reaction between the hours of about 6:00 a.m. and about 7:00 p.m.
An article of manufacture comprising:
Dependencies are inferred from the claim text.