Substituted aminoalkylaminopyridines

A compound of formula I

• in which
• R1 is hydrogen, 1-4C-alkyl, 1-4C-alkoxy, halogen, trifluoromethyl, wholly or predominantly fluorine-substituted 1-4C-alkoxy, chlorodifluoromethoxy or 2-chloro-1,1,2-trifluoroethoxy,
• R2 is hydrogen or 1-4C-alkyl,
• R3 is halogen or 1-4C-alkyl,
• R4 is 1-7C-alkyl,
• A is 1-7C-alkylene,
• X is N or CH, and
• n is the number 0, 1 or 2,
• and in which
• R5 is 1-7C-alkyl, 3-8C-cycloalkyl or Ar-1-4C-alkyl and
• R6 is 1-7C-alkyl, 3-8C-cycloalkyl or Ar-1-4C-alkyl,
• where
• Ar is phenyl, furyl, naphthyl, tetrahydronaphthyl, or phenyl which is substituted by R7, R8 and R9,
• or in which
• R5 and R6 together represent, with inclusion of the nitrogen atom to which both are bonded, an unsubstituted or substituted heterocyclic ring which is selected from the group consisting of pyrrolidine, piperidine, piperazine, morpholine, indoline, octahydro-1H-indole, 1,2,3,4-tetrahydroquinoline, 1,2,3,4-tetrahydroisoquinoline, decahydroquinoline and decahydroisoquinoline,
• where
• a substituted pyrrolidino radical is substituted by one or two identical or different substituents selected from the group consisting of 1-4C-alkyl, 1-4C-alkoxy, 1-4C-alkoxy-1-4C-alkyl, 1-4C-alkoxycarbonyl, 1-4C-alkylcarbonyloxy, hydroxy-1-4C-alkyl, hydroxyl and carboxyl,
• a substituted piperidino radical is substituted by one, two or three identical or different substituents selected from the group consisting of 1-4C-alkyl, gem.-di-1-4C-alkyl, 1-4C-alkoxy, 1-4C-alkoxy-1-4C-alkyl, 1-4C-alkoxycarbonyl, 1-4C-alkylcarbonyl, 1-4C-alkylcarbonyl-1-4C-alkyl, hydroxy-1-4C-alkyl, dihydroxy-1-4C-alkyl, di-1-4C-alkylamino, di-1-4C-alkylamino-1-4C-alkyl, pyrrolidino, piperidino, pyrrolidinyl-1-4C-alkyl, piperidinyl-1-4C-alkyl, carbamoyl, di-1-4C-alkylaminocarbonyl, piperidinocarbonyl, morpholinocarbonyl, phenyl, phenyl substituted by R7, R8 and R9, phenyl-1-4C-alkyl, benzoyl, benzoyl substituted by halogen, or formyl, carboxyl, cyano, hydroxyl, halogen and sulfo,
• a substituted piperazino radical can be substituted in position 2, 3, 5 or 6 by a 1-4C-alkyl radical and is substituted in position 4 by a substituent selected from the group consisting of 1-4C-alkyl, 3-7C-cycloalkyl, 3-7C-cycloalkyl-1-4C-alkyl, 1-4C-alkoxycarbonyl, 1-4C-alkoxycarbonyl-1-4C-alkyl, hydroxy-1-4C-alkyl, di-1-4C-alkylamino-1-4C-alkyl, halo-1-4C-alkyl, carbamoyl, phenyl, phenyl substituted by R7, R8 and R9, phenyl-1-4C-alkyl, phenyl-1-4C-alkyl substituted by R7, R8 and R9 in the phenyl radical, naphthyl, benzhydryl and benzhydryl substituted by halogen,
• a substituted morpholino radical is substituted by one or two identical or different 1-4C-alkyl radicals,
• a substituted 1-indolinyl radical can be substituted in position 2 and/or 3 by a carboxyl group or by one or two identical or different 1-4C-alkyl radicals, and can be substituted in the benzo moiety by one or two identical or different substituents selected from the group consisting of 1-4C-alkyl, halogen and nitro,
• a substituted 1,2,3,4-tetrahydroquinoline radical is substituted by one or two identical or different substituents selected from the group consisting of 1-4C-alkyl and halogen,
• a substituted 1,2,3,4-tetrahydroisoquinoline radical can be substituted on positions 1, 3 and/or 4 by one or two identical or different substituents selected from the group consisting of 1-4C-alkyl, carboxyl, phenyl, phenyl-1-4C-alkyl or phenyl which is substituted by R7, R8 and R9 in the phenyl radical, and can be substituted on the benzo moiety by one or two substituents selected from the group consisting of hydroxyl, 1-4C-alkoxy and di-1-4C-alkylamino,
• and where
• R7 is hydrogen, 1-4C-alkyl, 1-4C-alkoxy, 1-4C-alkylcarbonyl, halogen, 1-4C-alkylamino or nitro,
• R8 is hydrogen, 1-4C-alkyl, 1-4C-alkoxy, halogen or nitro,
• and
• R9 is hydrogen or trifluoromethyl,
• or a salt thereof.