P53 response genes
AssigneeBristol-Myers Squibb Company
InventorsLeonard Buckbinder, Randy Talbott, Bernd R. Seizinger, Nikolai Kley
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Abstract
Nucleic acid sequences, particularly DNA sequences, coding for all or part of p53 response protein PIGI-1, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials are disclosed. The invention also concerns polypeptide molecules comprising all or part of p53 response protein PIGI-1, and methods for producing these polypeptide molecules.
Claims22
An isolated nucleic acid molecule comprising a nucleic acid sequence coding for p53 response protein PIGI-1 shown in FIG. 7 (SEQ. ID NO:2).
A DNA molecule comprising a DNA sequence having all or part of the nucleotide sequence shown in FIG. 6 (SEQ. ID NO:1), wherein the DNA sequence having part of the nucleotide sequence shown in FIG. 6 (SEQ ID NO:1) is at least about 30 sequential nucleotides in length.
An expression vector comprising a DNA sequence coding for p53 response protein PIGI-1 shown in FIG. 7 (SEQ ID NO:2).
A vector comprising a DNA sequence having all or part of the nucleotide sequence as shown in FIG. 6 (SEQ ID NO:1), wherein the DNA sequence having part of the nucleotide sequence shown in FIG. 6 (SEQ NO:1) is at least about 30 sequential nucleotides in length .
Dependencies are inferred from the claim text.