Prevention of retinal injury and degeneration by specific factors
AssigneesRegeneron Pharmaceuticals, Inc., The Regents of the Univ. of California
InventorsMatthew M. LaVail, Roy H. Steinberg, George D. Yancopoulos
Life of this patent
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Abstract
Photoreceptor injury or cell death (retinal degeneration) is prevented by the introduction into the living mammalian eye of specific, survival-promoting factors. These specific factors prevent damage and degeneration of photoreceptors when introduced into the living eye prior to, during or after exposure to the damaging effects of light and delay photoreceptor damage caused by inherited disease.
Claims8
A method of reducing the degeneration of photoreceptors in a patient exposed to an environmental condition or having a pathological condition which causes such degeneration comprising administering into the eye of said patient an effective amount of CNTF.
A method of promoting the regeneration of outer segments of photoreceptors in a patient exposed to an environmental condition or having a pathological condition which causes photoreceptor degeneration comprising administering into the eye of said patient an effective amount of CNTF.
Dependencies are inferred from the claim text.