Thermal granulation process

Process for the production of directly tablettable granules containing an active compound having a melting point between 40.degree. and 150.degree. C. and tablet auxiliaries, which comprises forming a mixture of said active compound and said auxiliaries, heating said mixture to a temperature of from 40.degree. to 200.degree. C. in a melt extruder to melt a part of said active compound and form a mixture of said active compound and said auxiliaries wherein a part of said active compound is in the form of a melt, and extruding said mixture in which said active compound is present partly in the form of a melt, to produce a homogeneous non-agglutinating extrudate, and then comminuting said extrudate to form granules.