Banded prolonged release active agent dosage form
AssigneeAlza Corporation
InventorsPatrick S.-L. Wong, David Emil Edgren, Liang C. Dong, Vincent Joseph Ferrari
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Abstract
The present invention is directed to an active agent dosage form which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface two or more insoluble bands. The invention is also directed to the method for making the active agent dosage form.
Claims10
An active agent dosage form for delivering an active agent formulation to a fluid environment of use over a prolonged period of time comprising:
- a) an active agent formulation;
- and
- b) an insoluble material for protecting a plurality of discrete portions of the surface of the active agent formulation;
- wherein the amount of surface area unprotected by the insoluble material is greater than the amount of surface area protected by the insoluble material.
A method for obtaining release of an active agent formulation into a fluid environment of use from a dosage form over a prolonged period of time comprising:
- a) protecting a plurality of discrete portions of the surface of the active agent formulation from contact with the fluid environment of use, the amount of surface area remaining unprotected being greater than the amount of surface area being protected;
- and
- b) increasing the surface area of the dosage form over the prolonged period of time by transporting portions of the unprotected active agent formulation into the fluid environment of use.
Dependencies are inferred from the claim text.