Method for treating headache pain with topical local anesthetic compositions
OwnerLarry J. Caldwell, Bradley Stuart Galerinventors
Life of this patent
Estimating the term…
Abstract
Methods are provided for the treatment of a host suffering from head ache pain with topical applications of a local anesthetic. The topical local anesthetic composition comprises an effective amount of a local anesthetic in combination with eucalyptol as a penetration enhancing agent, and optionally an additional penetration enhancing agent. The topical local anesthetic composition is applied to a keratinized skin site proximal to target nerves associated with the headache pain, usually to the supraorbital or occipital regions of the head. Upon application of the topical composition, the local anesthetic rapidly penetrates the skin to block conduction in the target nerves and provide pain relief to the host.
Claims10
A method for treating a host suffering from headache pain by blocking conduction in occipital and supraorbital nerves associated with said headache pain, said method comprising:
- applying at a keratinized skin site proximal to said target nerves in the supraorbital or occipital regions of the head of said host a topical local anesthetic composition comprising:
- an effective amount of local anesthetic wherein said local ansthetic is an amine linked through a connecting group to an aromatic group in combination with eucalyptol as a penetration enhancing agent;
- whereby said local anesthetic rapidly penetrates the skin surface at said skin site to block conduction in said occipital or target nerves and said host experiences at least a partial subsidence in the intensity of said headache pain.
A method for treating a host suffering from headache pain by blocking conduction in target nerves associated with said headache pain, said method comprising:
- applying at a keratinized skin site proximal to said target nerves a topical local anesthetic composition comprising:
- (a) an effective amount of a local anesthetic, wherein said local anesthetic is an amine linked through a connecting group to an aromatic group;
- (b) eucalyptol as a penetration enhancing agent and (c) an additional penetration enhancing agent, wherein said target nerves are selected from the group consisting of occipital and supraorbital nerves;
- whereby said local anesthetic rapidly penetrates the skin at said skin site to block conduction in said target nerves and said host experiences at least a partial subsidence in the intensity of said headache pain.
A method for treating a host suffering from headache pain by blocking conduction in target nerves selected from the group consisting of the occipital and supraorbital nerves, said method comprising:
- applying at a keratinized skin site proximal to said target nerves a topical local anesthetic composition comprising:
- (a) an effective amount of benzocaine, (b) eucalyptol and (c) N,N-diethyl-m-toluamide;
- whereby said benzocaine rapidly penetrates the skin at said skin site to block conduction in said target nerves and said host experiences at least a partial subsidence in the intensity of said headache pain.
Dependencies are inferred from the claim text.