Wound dressings
AssigneeUniversity College Cardiff Consultants Limited
InventorsMichael Fowler, Thomas Richard Burrow, Terence Dudley Turner, Ryszard Jan Schmidt, Lip Yong Chung
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Abstract
A wound dressing comprises a chemically modified polymer which has a free radical activity in the DPPH Test in the range 15-80 percent. It may comprise a chemically modified polymer which carries at least one chemical group which is a persistent free radical or a precursor therefor. It may comprise a chemically modified polymer which carries at least one chemical group capable of reacting with molecular oxygen in a wound environment to form hydrogen peroxide. It may comprise a chemically modified polymer capable of stimulating the activity of macrophages or the proliferation of fibroblasts or both in a wound environment.
Claims6
A wound dressing which comprises an addition polymer having hydroxyl, carbonyl or amide functional groups or a polysaccharide having hydroxy functional groups, said functional groups having been converted to derivatives which are persistent free radicals or precursors of persistent free radicals, which free radicals are reactive with molecular oxygen in a mammalian wound environment comprising macrophages and/or fibroblasts, said reaction being such as to form hydrogen peroxide in said environment;
- wherein said polymer stimulates activity of said macrophages or proliferation of said fibroblasts in said wound environment.
Dependencies are inferred from the claim text.