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US 5,667,487 AGranted
Ionosonic drug delivery apparatus
OwnerJulian L. Henleyinventor
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OwnerJulian L. Henleyinventor
Estimating the term…
An improved apparatus for the iontophoretic-ultrasonic (ionosonic) transdermal delivery of medication across the skin or other biological membrane so the medication can be absorbed by the adjacent tissues and blood vessels. The apparatus can be adapted for large dermal area application or for a smaller area of application, depending on the choice of specific electrode employed. The apparatus comprises a multichannel iontophoretic applicator electrode. Multiple piezoelectric elements are mounted on the ionotophoetic electrode. The combination of ultrasonic vibration and iontophoresis creates a significant improvement in the penetration of medicament in contact with the skin or mucous membrane underlying the electrode. Drug delivery systems employing biofeedback such as the transcutaneous delivery of insulin based on tissue glucose are outlined based on this ionosonic technology.
An ionosonic medicament applicator for use with a multichannel power source and adapted to be releasably attached to the skin of an organism for the transdermal delivery of medicament, comprising in combination:
A method for transdermally administering medicament to a patient comprising the steps of:
An ionosonic medicament applicator for use with a multichannel power source and adapted to be releasably attached to the skin of an organism for the transdermal delivery of medicament, comprising in combination:
Dependencies are inferred from the claim text.