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US 5,665,765 AGranted
5,6,7,8-tetrahydronaphtho[2,3-b]furan and indano[5,6-b]furan amine compounds
AssigneeAdir et Compagnie
InventorsJean-Louis Peglion, Joel Vian, Aimee Dessinges, Mark Millan, Valerie Audinot
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Abstract
New compounds of formula: ##STR1## wherein: A-B, n and Y are as defined in the description, their optical isomers and physiologically tolerable salts thereof with appropriate acids. The products of the invention may be used as medicaments.
Claims7
A compound selected from the group consisting of those of formula I:
- ##STR15## wherein:
- A-B represents CH.dbd.CH or CH.sub.2 -CH.sub.2 ;
- n represents zero or one;
- and
- Y represents:
- (C.sub.2 -C.sub.10)alkenyl in straight or branched chain;
- .omega.-(cycloalkyl)alkyl, .omega.-(methylcycloalkyl)alkyl, or .omega.,.omega.-(dicycloalkyl)alkyl in each of which each cycloalkyl contains 3 to 7 carbon atoms inclusive, and the alkyl moiety contains 1 to 4 carbon atoms inclusive in straight or branched chain;
- or
- a group of formula:
- ##STR16## wherein:
- p is an integer of 1 to 4 inclusive,
- R.sub.1 represents hydrogen, halogen, hydroxy, or methoxy,
- R.sub.2 represents halogen, hydroxy, (C.sub.1 -C.sub.5)alkoxy, phenyl, --NH--CO--CH.sub.3, --NH--CO--CF.sub.3, or --NH--SO.sub.2 --CH.sub.3, and
- R.sub.3 represents halogen, (C.sub.1 -C.sub.5)alkoxy, trifluoromethyl, cyano, phenyl, p-aminophenyl, or p-acetylphenyl;
- in racemic form or in the form of optical isomers;
- and addition salts thereof with pharmaceutically-acceptable acids.
13 more elements
Dependencies are inferred from the claim text.