Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides

A copolymer comprising an N-acylated derivative of poly(2-amino-2-deoxy-D-glucose), wherein between 1 and 50 percent of the free amines of said poly(2-amino-2-deoxy-D-glucose) are acylated with a first acyl group, said first acyl group is COE.sub.1 where E.sub.1 is selected from the group consisting of C.sub.3-33 carboxyalkyl, C.sub.3-33 carboxyalkenyl, C.sub.7-39 carboxyarylalkyl, and C.sub.9-39 carboxyarylalkenyl, between 50 and 99 percent of the free amines of said poly(2-amino-2-deoxy-D-glucose) are acylated with a second acyl group, said second acyl group is COE.sub.2 where E.sub.2 is selected from the group consisting of C.sub.1-30 alkyl, C.sub.2-30 alkenyl, C.sub.6-37 arylalkyl, and C.sub.8-37 arylalkenyl, provided at least one of the free amines of said poly(2-amino-2-deoxy-D-glucose) is acylated with said first acyl group, and the hydroxy groups of said poly(2-amino-2-deoxy-D-glucose) are free or up to 30 percent of them are acylated with said first acyl group or said second acyl group.