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US 5,665,592 AGranted
Feline immunodeficiency virus isolate NCSU.sub.1
AssigneeNorth Carolina State University
InventorsWayne A. F. Tompkins, Mary B. Tompkins
Life of this patent
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AssigneeNorth Carolina State University
InventorsWayne A. F. Tompkins, Mary B. Tompkins
Estimating the term…
Disclosed is an isolated and purified feline immunodeficiency virus (FIV) culture having the identifying characteristics of FIV isolate NCSU.sub.1. A biologically pure culture of host cells containing a FIV having the identifying characteristics of FIV isolate NCSU.sub.1 is also disclosed, along with isolated and purified DNA coding for (a) an FIV having the identifying characteristics of FIV isolate NCSU.sub.1, or (b) an antigenic fragment of an FIV having the identifying characteristics of FIV isolate NCSU.sub.1. Various vaccine formulations containing active agents derived from the foregoing FIV virus, DNA encoding the virus, and DNA encoding antigenic fragments of the virus are also disclosed herein. Also disclosed are immunodeficient mice containing feline tissue, which feline tissue is capable of infection with a feline immunodeficiency virus such as (but not limited to) FIV isolate NCSU.sub.1.
Isolated DNA coding for feline immunodeficiency virus NCSU.sub.1 (ATCC deposit number VR2333).
An isolated DNA molecule encoding a feline immunodeficiency virus (FIV) having all the biological properties of feline immunodeficiecy virus NCSU.sub.1 (ATCC deposit number VR2333), said isolated DNA molecule comprising a group antigen (gag) gene having a DNA sequence selected from the group consisting of:
An isolated DNA molecule encoding a feline immunodeficiecy virus (FIV) group-antigen (gag) polypeptide, said isolated DNA molecule selected from the group consisting of:
Dependencies are inferred from the claim text.