Isolation and characterisation of genes resistant to anthracycline antibiotics
AssigneePharmacia & Upjohn Company
InventorsMarinella Caruso, Anna Luisa Colombo, Luisa Garofano, Francesca Torti, Guiseppe Zanella
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Abstract
Doxorubicin resistance can be conferred on a host by transforming the host with a recombinant vector comprising a DNA having the configuration of restriction sites shown in FIGS. 1 or 2 of the accompanying drawings or a restriction fragment derived therefrom containing a gene coding for doxorubicin resistance.
Claims17
An isolated DNA molecule which is a DNA molecule having the restriction enzyme map shown in FIG. 1 or in FIG. 2, wherein said DNA molecule comprises a gene encoding doxorubicin resistance and is derived from Streptomyces peucetius.
Dependencies are inferred from the claim text.