Autologous dermal fibroblasts for the repair of skin and soft tissue defects
AssigneeIsolagen Technologies, Inc.
InventorWilliam K. Boss, Jr.
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Abstract
The application concerns a method of repairing sequelae of acne vulgaris in a subject which comprises the steps of: a) providing a fibroblast-seeded clot having dermal fibroblasts derived from the subject, said fibroblasts being substantially free of cells other than fibroblasts, and said clot being substantially free of proteins that are immunogenic in the subject; b) abrading a site of sequelae of acne vulgaris of a subject to the level of the middle or deep dermis; and c) applying the clot to the abraded site, so that the seeded fibroblasts are juxtaposed to dermis.
Claims1
A method of repairing sequelae of acne vulgaris in a subject which comprises the steps of:
- a) providing a fibroblast-seeded clot having dermal fibroblasts derived from the subject, said fibroblasts being substantially free of cells other than fibroblasts, and said clot being substantially free of proteins that are immunogenic in the subject;
- b) abrading a site of sequelae of acne vulgaris of a subject to the level of the middle or deep dermis;
- and
- c) applying the clot to the abraded site, so that the seeded fibroblasts are juxtaposed to dermis.
Dependencies are inferred from the claim text.