Cholesterol-lowering drug
AssigneeHisamitsu Pharmaceutical Co., Inc.
InventorsMinenobu Okayama, Shuji Sato
Life of this patent
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Abstract
A cholesterol-lowering drug which comprises, as the main ingredient, a non-crosslinked anion exchange resin consisting of structural units represented by the general formula (I): ##STR1## wherein R.sub.1 represents a benzyl group or an alkyl group having 1 to 20 carbon atoms, R.sub.2 and R.sub.3 may be identical with, or different from, each other and each represent a lower alkyl group having 1 to 4 carbon atoms, R.sub.4 represents a hydrogen atom or a lower alkyl group, X represents a physiologically acceptable counter ion, n is an integer of from 1 to 3, and p is an average degree of polymerization ranging from 10 to 10,000.
Claims6
A pharmaceutical drug composition for lowering the cholesterol content in a patient which contains as the main active component a non-crosslinked anion exchange resin, said anion exchange resin being a homopolymer obtained from the polymerization of a member selected from the group consisting of acryloyloxyethyltrimethylammonium chloride, acryloyloxyethyl-N,N-dimethylbenzyl-ammonium chloride and acryloyloxyethyl-N,N-dimethylhexylammonium chloride, the degree of polymerization being between 10 and 10,000.
The method of treatment of a patient suffering from high blood cholesterol level which consists of administering to said patient a cholesterol-lowering drug composition which contains a non-crosslinked anion exchange resin as the main active component, said anion exchange resin being a homopolymer obtained from the polymerization of a member selected from the group consisting of acryloyloxyethyltrimethylammonium chloride, acryloyloxyethyl-N,N-dimethylbenzylammonium chloride and acryloyloxyethyl-N,N-dimethylhexylammonium chloride, the degree of polymerization being between 10 and 10,000, said drug composition being administered in unit dosage form containing from 0.01 to 3.0 g, once to thrice a day, for at least a period of time sufficient to cause a decrease in the blood cholesterol level.
Dependencies are inferred from the claim text.