Fused cycloalkylimidazopyridines
AssigneeMinnesota Mining and Manufacturing Company
InventorsNick Nikolaides, John F. Gerster
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Abstract
6,7-propylene-, butylene-, or pentylene-bridged imidazopyridin-4-amines that induce interferon (.alpha.) biosynthesis in human cells, their pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis and treating viral infections involving the use of such compounds are disclosed.
Claims1
A compound of the formula ##STR8## wherein n is 1, 2, or 3, R.sub.3 is selected from the group consisting of hydrogen, fluoro, chloro, straight chain or branched chain alkyl containing one to about four carbon atoms, and straight chain or branched chain fluoro- or chloroalkyl containing one to about four carbon atoms and at least one fluorine or chlorine atom, R.sub.a is a group that renders the associated ester group susceptible of nucleophilic attack by an anion derived from an active methylene compound, and R.sub.b is a group that renders the associated ester group susceptible of hydrolysis.
Dependencies are inferred from the claim text.