Nucleic acids encoding hepatocyte growth factor receptor antagonist antibodies
AssigneeGenentech, Inc.
InventorsRalph H. Schwall, Kelly Helen Tabor
Life of this patent
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Abstract
Hepatocyte growth factor (HGF) receptor antagonists are provided. The HGF receptor antagonists include HGF receptor antibodies and fragments thereof. The HGF receptor antagonists can be employed to block binding of HGF to HGF receptors or substantially inhibit HGF receptor activation. The HGF receptor antagonists may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treating cancer using the HGF receptor antagonists are also provided.
Claims12
An isolated nucleic acid encoding a hepatocyte growth factor (HGF) receptor antagonist which is a monovalent antibody that specifically hinds to a HGF receptor.
Dependencies are inferred from the claim text.