Tissue graft and method for urinary urothelium reconstruction replacement
AssigneesPurdue Research Foundation, Methodist Hospital of Indiana, Inc.
InventorsPeter M. Knapp, Jr., James E. Lingeman, Robert J. Demeter, Stephen F. Badylak
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Abstract
A method for surgical repair of a diseased or damaged bladder is described. Diseased or damaged bladder tissue is surgically replaced with submucosal tissue of a warm blooded vertebrate to promote regrowth of endogenous urinary bladder tissue.
Claims3
A method of repairing a damaged or diseased portion of a urinary bladder by promoting the growth of endogenous urinary bladder tissues having a urine impermeable layer and a functional muscle layer which comprises
- a) surgically removing the damaged or diseased portion of the urinary bladder and
- b) replacing the removed portion of the bladder with a tissue graft construct comprising intestinal submucosa delaminated from both the tunica muscularis and the luminal portion of the tunica mucosa.
A method of repairing a damaged or diseased portion of a urinary tract by promoting the growth of endogenous urothelial tissues having a urine impermeable layer and a functional muscle layer which comprises
- a) surgically removing the damaged or diseased portion of the urinary tract and
- b) replacing the removed portion of the tract with a tissue graft construct comprising intestinal submucosa delaminated from both the tunica muscularis and the luminal portion of the tunica mucosa.
Dependencies are inferred from the claim text.