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AssigneeBehringwerke Aktiengesellschaft
InventorsWolfgang Bredt, Bernhard Gerstenecker, Enno Jacobs, Wilhelm Schuy
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The invention relates to monoclonal antibodies and fragments thereof which are specific for Mycoplasma pneumoniae P2 protein and have a cross-reactivity of 1% or less with five other species of the genus Mycoplasma and other pathogen species of the concomitant flora, and to methods for the preparation of the monoclonal antibodies according to the invention. The invention furthermore relates to hybridomas which produce the antibodies according to the invention, and to methods for the preparation thereof. Finally, the invention relates to the use of the monoclonal antibodies according to the invention for detecting Mycoplasma pneumoniae in a sample.
A monoclonal antibody or fragments thereof, which react specifically with P1 protein of Mycoplasma pneumoniae and show a cross-reactivity of 1% or less with five other species of the genus Mycoplasma.
The hybridoma M57 deposited as ECACC accession number 91041010.
The hybridoma P1.27 deposited as ECACC accession number 91041013.
The hybridoma M75 deposited as ECACC accession number 91052310.
A monoclonal antibody and fragments thereof, which react specifically with P1 protein of Mycoplasma pneumoniae and show a cross-reactivity of 1% or less with the species M. genitalium, M. hominis, M. fermentens, M. salivarium, and M. orale of the species of the genus Mycoplasma.
Dependencies are inferred from the claim text.