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AssigneeColetica
InventorsMarie-Christine Levy, Florence Edwards-Levy, Isabelle Orly
Estimating the term…
Particles, preparation methods therefor, and compositions containing same. The particles include at least one esterified polysaccharide and at least one polyamine, as well as at least one gellable polysaccharide when neither the esterified polysaccharide nor the polyamine can be gelled under the selected operating conditions. Said particle includes, at least on its surface, a membrane consisting of the product of the transacylation reaction between the esterified polysaccharide and said polyamine within an optionally gellable gel, said reaction causing the formation of covalent amide bonds. Such particles may be used to encapsulated various active principles useful in the fields of cosmetics, pharmaceuticals and agri-foodstuffs, enzymes, cells and micro-organisms.
A particle comprising at least one esterified polysaccharide and at least one polyamine, and further a gellable polysaccharide when neither the esterified polysaccharide nor the polyamine arc gellable under the conditions used for preparing said particle, said particle comprising, at least an outer membrane formed by a transacylation reaction with formation of covalent amide bonds between the esterified polysaccharide and the polyamine.
The particle of claim 11, in the form of of a bead, capsule, a microcapsule, a sphere or a microsphere.
The particle of claim 11, wherein said polysaccharide is a gellable polysaccharide selected from the group consisting of an alginate, a carrageenan, a gellable pectin, and a polysaccharide bearing amino groups gellable at a pH above about 6.2 or in the presence of a polyphosphate.
A process for the manufacture of particles comprising the following successive steps:
A composition selected from the group consisting of a cosmetic, a pharmaceutical, a therapeutic, a food, an enzymatic composition, a composition for cell therapy, a composition for enzyme therapy, a composition for blood purification, a composition for reagents, a composition for toxicological tests in vitro, a composition for agriculture, a composition for coated seeds, a composition for biotechnological production containing particles comprising at least one esterified polysaccharide and at least one polyamine, and further a gellable polysaccharide when neither the esterified polysaccharide nor the polyamine are gellable under the conditions used for preparing said particle, said particle comprising, at least an outer membrane formed by a transacylation reaction with formation of covalent amide bonds between the esterified polysaccharide and the polyamine.
Dependencies are inferred from the claim text.