Back to results
US 5,635,399 AGranted
Retroviral vectors expressing cytokines
AssigneeChiron Corporation
InventorsMichael Kriegler, Francis P. McCormick
Life of this patent
Estimating the term…
Abstract
A drug delivery virion which contains an expression system for the desired protein active ingredient packaged in an envelope derived from a retrovirus is especially useful in administering materials which need to cross cell membranes in order to serve their function.
Claims8
A replication defective retroviral particle capable of infecting a human cell, said retroviral particle having an RNA sequence therein encoding a human protein, said RNA sequence operably linked to a promoter and expressible in said human cell, said protein being a cytokine or tissue plasminogen activator.
Dependencies are inferred from the claim text.