Back to results
US 5,635,357 AGranted
Stabilized microspheres and methods of preparation
AssigneeBecton, Dickinson and Company
InventorsAdrien Malick, Hans H. Feindt
Life of this patent
Estimating the term…
Abstract
Stabilized microspherical particles having hydrophobic liquid cores prepared as oil-in-water microemulsions. The particles are stabilized by a surface layer comprising an amphiphilic compound and may be functionalized to allow covalent coupling of a ligand to the surface of the particle. When used as tracers in assays, a water insoluble dye may be incorporated in the core liquid of the microparticles.
Claims7
A composition comprising microspherical particles, the particles comprising:
- a) a hydrophobic core comprising a liquid silicone or fluorosilicone, and;
- b) an amphiphilic compound, the amphiphilic compound forming a monolayer on the surface of the particles.
Dependencies are inferred from the claim text.