Anti-oncoimmunin-M antibodies and uses thereof

An antibody or binding fragment thereof, that specifically binds a substantially pure oncoimmunin-myeloid (OI-M) factor, said factor comprising the polypeptide sequences of SEQ ID No. 1 and SEQ ID No. 2, wherein said factor is derived from a tumor cell line, and said factor has a molecular weight of about 36 kDa by SDS-PAGE analysis and said factor has the ability to inhibit growth in a myeloid cell line or induce differentiation of a myeloid cell line in an interleukin-2 and interleukin-4 free, serum-free medium, and wherein said antibody or binding fragment thereof is derived from a mammal immunized with said oncoimmunin-myeloid factor.