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US 5,635,344 AGranted
Shipping medium for organ-derived cells
AssigneeCedra Corp.
InventorsDavid B. Garcia, Enrique Chacon
Life of this patent
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AssigneeCedra Corp.
InventorsDavid B. Garcia, Enrique Chacon
Estimating the term…
A medium for the shipment and preservation of organ-derived cells and method for its use. The shipping medium is in a firm, substantially semi-solid state at ambient and chilled temperatures, but becomes substantially fluid upon reaching body temperature. The medium in its fluid state can be poured over cultured cells or tissue slices or used to suspend isolated cells and then can be chilled to reach its semi-solid state for shipment. The firm, semi-solid nature of the medium and the presence of various components preserves organ-derived cells for a longer period of time during shipping than the preservation time achieved by using conventional liquid medium, better protects the organ-derived cells during shipment, effectively eliminates spillage during transport, and is easily used by researchers who supply preserved organ-derived cells as well as by researchers who receive the preserved organ-derived cells for experimentation or research.
A biological matrix for shipping organ-derived cells, which biological matrix comprises cell preservation medium for preserving organ-derived cells and further comprises a congealing substance in an amount sufficient to cause said biological matrix to be in a substantially fluid state when the temperature of said matrix is about 40.degree. C., to congeal when the temperature of said matrix is lowered to about 5.degree. C. and to return to a substantially fluid state when the temperature of said matrix is raised to about 40.degree. C.
A biological matrix for shipping organ-derived cells, which biological matrix comprises cell preservation medium for preserving organ-derived cells, 0.1 g/L-1.0 g/L Adenosine, 0.05 g/L-0.5 g/L Glycine, a congealing substance in an amount sufficient to cause said biological matrix to be in a substantially fluid state when the temperature of said matrix is about 40.degree. C., to congeal when the temperature of said matrix is lowered to about 5.degree. C. and to return to a substantially fluid state when the temperature of said matrix is raised to about 40.degree. C.;
Dependencies are inferred from the claim text.