Method of treating cancer by conjunctive therapy with N,N'-bis[3-(ethylamino)propyl]-1,7-heptanediamine and a cytotoxic agent
AssigneeMerrell Pharmaceuticals Inc.
InventorsNellikunja J. Prakash, Terry L. Bowlin
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Abstract
The present invention relates to a method of treating a patient suffering from a neoplastic disease state comprising administering to said patient an effective antineoplastic amount of N,N'-bis[3-(ethylamino)propyl]-1,7-heptanediamine in conjunctive therapy with an effective antineoplastic amount of a cytotoxic agent selected from the group consisting of an antineoplastic vinca alkaloid, an antineoplastic antibiotic, an antineoplastic antimetabolite and an antineoplastic platinum coordination complex, wherein a synergistic antineoplastic effect results.
Claims12
A method of treating a patient suffering from a neoplastic disease state comprising administering to said patient an effective antineoplastic amount of N,N'-bis[3-(ethylamino) propyl]-1,7-hepanediamine and an antineoplastic platinum coordination complex selected from the group consisting of cisplatin and carboplatin wherein a synergistic antineoplastic effect results.
Dependencies are inferred from the claim text.