Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same
AssigneesBioSepra, Inc., Assistance Publique-Hopitaux de Paris
InventorsEgisto Boschetti, Michel Brouard, Ludovic Drouet, Pierre Girot, Alexandre Laurent, Michel Wassef
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Abstract
The present invention concerns the use of microspheres for therapeutic embolization consisting of a hydrophilic acrylic copolymer coated with a cell adhesion promoter.
Claims12
A microsphere, having a diameter ranging between about 10 to about 2000 .mu.m, useful for embolization which comprises a hydrophilic acrylic copolymer coated with a cell adhesion promoter and a marking agent.
A microsphere having a diameter ranging between about 10 to about 2000 .mu.m, useful for embolization, which comprises a copolymer comprising, in copolymerized form, about 25 to about 98% neutral hydrophilic acrylic monomer by weight, about 2 to about 50% difunctional monomer by weight, about 0 to about 50% by weight of one or more monomers having a cationic charge, and about 1 to about 30% by weight of a functional monomer making possible the detection of the microsphere, coated with a cell adhesion promoter.
A microsphere having a diameter ranging between about 10 to about 2000 .mu.m, useful for embolization, which comprises a copolymer comprising, in copolymerized form, about 25 to about 98% neutral hydrophilic acrylic monomer by weight, about 2 to about 50% difunctional monomer by weight, about 0 to about 50% by weight of one or more monomers having a cationic charge, a marking agent and a cell adhesion promoter.
Dependencies are inferred from the claim text.