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AssigneeYale University
InventorsMarek J. Maryanskl, John C. Gore, Robert Schulz
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A visible and/or MRI visualizable permanent image is formed in a gel in a container which maintains the gel a dimensionally stable shape, which gel contains uniformly dispersed therein in storage stable form at least one radiant energy, e.g., ionizing radiation, or mechanical, e.g., ultrasonic or sonic shock wave, polymerizable monomer in a concentration effective to form a polymer in the gel which alters the NMR relaxation time of the solvent in any area thereof in which the polymer is formed, e.g., a mixture of (a) a linearly homopolymerizable monomer and (b) a comonomer which is cross-linkably copolymerizable with the monomer, the polymerization of the monomer initiated by the radiant or mechanical energy being restricted to any area of the gel which receives that energy, which image is representative of the dose distribution of the energy to which the gel is exposed, by exposing the gel to a non-uniform dose of the energy until a polymer which produces a permanent image representative of the dose of the energy received by the gel is formed therein. The image can be used for dosimetric purposes; to provide reference standards for quality control of magnetic resonance imaging techniques and equipment; and as a three- or two-dimensional array detector in industrial radiography (nondestructive testing techniques).
A method of detecting, measuring and displaying a non-uniform dose of radiant or mechanical energy by forming a visible and/or MRI visualizable permanent 3-dimensional image in a gel which is representative of the 3-D distribution of the dose of the radiant or mechanical energy to which the gel is exposed, which comprises exposing a dimensionally stable gel which contains uniformly dispersed therein in storage stable form at least one monomer which is polymerizable in the gel by the radiant or mechanical energy, in a concentration effective when thus polymerized to produce a polymer in the gel which precipitates therefrom and/or which alters the NMR relaxation time of the solvent phase of the gel in any area thereof in which the polymer is formed, to a non-uniform dose of radiant or mechanical energy until a permanent image representative of that energy is formed in the gel.
An article of manufacture comprising a gel which is adapted for use as a radiation dosimeter for detecting, measuring and displaying a dose of radiant or mechanical energy by forming a visible and/or MRI visualizable permanent three-dimensional image therein which is representative of the distribution of a dose of radiant or mechanical energy to which the article is exposed, which comprises a gel which is maintained in a dimensionally stable shape and contains uniformly dispersed therein in storage stable form at least one radiant or mechanical energy polymerizable monomer, in a concentration effective when thus polymerized to produce a polymer in the gel which is insoluble therein or alters the NMR relaxation time of the solvent in any area thereof in which the polymer is formed.
A method of quality control for magnetic resonance imaging techniques and NMR equipment performance which comprises forming an image in a gel as a reference image for comparison with another image obtained by or as a standard for magnetic resonance imaging, wherein said image in a gel is formed by exposing a dimensionally stable gel which contains uniformly dispersed therein in storage stable form at least one monomer which is polymerizable in the gel by the radiant or mechanical energy, in a concentration effective when thus polymerized to produce a polymer in the gel which precipitates therefrom and/or which alters the NMR relaxation time of the solvent phase of the gel in any area thereof in which the polymer is formed, to a non-uniform dose of radiant energy until a permanent image representative of that energy is formed in a gel.
A method of nondestructive testing of a three-dimensional solid object which comprises subjecting the object to a dose of radiant energy and forming an image in a gel from the radiant energy which is not absorbed by the object or which is deflected or reflected thereby, wherein said image in a gel is formed by exposing a dimensionally stable gel which contains uniformly dispersed therein in storage stable form at least one monomer which is polymerizable in the gel by the radiant or mechanical energy, in a concentration effective when thus polymerized to produce a polymer in the gel which precipitates therefrom and/or which alters the NMR relaxation time of the solvent phase of the gel in any area thereof in which the polymer is formed, to a non-uniform dose of radiant energy until a permanent image representative of that energy is formed in a gel.
Dependencies are inferred from the claim text.