Method for producing 1,2-benzisothiazol-3-ones
AssigneeSumitomo Seika Chemicals Co., Ltd.
InventorsHirokazu Kagano, Hiroshi Goda, Katsuhiko Yoshida, Mikio Yamamoto, Shigeki Sakaue
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Abstract
A method for producing a 1,2-benzisothiazol-3-one, having the steps of carrying out a reaction of a 2-(alkylthio)benzaldehyde with a hydroxylamine to give a 2-(alkylthio)benzaldehyde oxime and carrying out a reaction of the 2-(alkylthio)benzaldehyde oxime with a halogenating agent; and a method for producing a 1,2-benzisothiazol-3-one, having the steps of carrying out a reaction of a 2-halobenzonitrile with an alkanethiol in a heterogeneous solvent system in the presence of a base to give a 2-(alkylthio)benzonitrile and carrying out a reaction of the 2-(alkylthio)benzonitrile with an halogenating agent in the presence of water.
Claims4
A method for producing a 1,2-benzisothiazol-3-one represented by the formula (III), comprising carrying out a reaction of a 2-(alkylthio)benzonitrile represented by the following formula (IV):
- ##STR20## wherein R.sup.1 represents an alkyl group having 1 to 4 carbon atoms, and R.sup.2 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a nitro group, a carboxyl group, methoxy carboxyl, ethoxylcarboxyl, propoxycarboxyl, butoxycarboxyl, or a halogen atom, with a halogenating agent selected from the group consisting of chlorine, bromine, sulfuryl chloride and sulfuryl bromide in the presence of water to give a 1,2-benzisothiazol-3-one represented by the following general formula (III):
- ##STR21## wherein R.sup.2 is defined as above.
Dependencies are inferred from the claim text.