Certain aminomethyl phenylimidazole derivatives; and 4-aryl substituted piperazinyl and piperidinylmethyl phenylimidazole derivatives; a new class of dopamine receptor subtype ligands

A compound of the formula:

• ##STR38## or the pharmaceutically acceptable non-toxic alts thereof wherein:
• W is CH or N;
• R.sub.1 and T are the same or different and represent hydrogen, halogen, hydroxy, straight or branched chain lower alkyl having 1-6 carbon atoms, or straight or branched chain lower alkoxy having 1-6 carbon atoms;
• X represents hydrogen, halogen, hydroxy, straight or branched chain lower alkyl having 1-6 carbon atoms, or straight or branched chain lower alkoxy having 1-6 carbon atoms;
• Y is hydrogen, halogen, amino, or straight or branched chain lower alkyl having 1-6 carbon atoms;
• and
• R.sub.7 represents hydrogen, or phenyl or benzyl where the phenyl group of each is unsubstituted or substituted with halogen, alkoxy, or alkyl.

A compound of the formula:

• ##STR39## wherein:
• R.sub.1 and T independently represent hydrogen, halogen, hydroxy, lower alkyl, or lower alkoxy;
• X, Y and Z independently represent hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, or --SO.sub.2 R.sub.6 where R6 is lower alkyl;
• and
• E is CH or nitrogen.

A compound of the formula:

• ##STR40## wherein:
• R.sub.1 and T independently represent hydrogen, halogen, hydroxy, lower alkyl, or lower alkoxy;
• X, Y and Z independently represent hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, or --SO.sub.2 R.sub.6 where R6 is lower alkyl;
• n is 0 or 1;
• and
• A and Q are the same or different and represent CH or nitrogen.