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US 5,633,372 AGranted
Heterocycle based nitrogen sulfur ligands useful in radiographic imaging agents
AssigneeMallinckrodt Medical, Inc.
InventorsRaghavan Rajagopalan, Ananthachari Srinivasan
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Abstract
The present invention relates particularly to novel heterocycle based nitrogen-sulfur ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes.
Claims2
A ligand useful in forming radionuclide complexes, said ligand having the general formula:
- ##STR14## wherein R.sup.1 is a suitable sulfur protecting group selected form the group consisting of benzoyl and tetrahydropranyl.
A ligand useful in forming radionuclide complexes, said ligand having the general formula:
- ##STR15## wherein R.sup.1 is a suitable sulfur protecting group selected from the group consisting of benzoyl and tetrahydropyranyl;
- and K is 2 or 4 and X is amino, carboxyl or hydroxyl.
Dependencies are inferred from the claim text.