Detection of amplified or deleted chromosomal regions
AssigneeThe Regents of the University of California
InventorsTrond Stokke, Daniel Pinkel, Joe W. Gray
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Abstract
The present invention relates to in situ hybridization methods for the identification of new chromosomal abnormalities associated with various diseases. In particular, it provides probes which are specific to a region of amplification in chromosome 20.
Claims11
A kit for the detection of an amplification at about position FLpter 0.85 on human chromosome 20, the kit comprising a compartment which contains a composition consisting essentially of one or more nucleic acid probes, each of which binds selectively to a target polynucleotide sequence at about FLpter 0.85 on human chromosome 20.
A composition consisting essentially of one or more nucleic acid probes, each of which binds selectively to a target polynucleotide sequence at about FLpter 0.85 on human chromosome 20.
Dependencies are inferred from the claim text.