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US 5,633,264 AGranted
Individual stereoisomers of 7-[3-(1-aminoalkyl)-1-pyrrolidinyl]-Quinolones and naphthyridones as antibacterial agents
AssigneeWarner-Lambert Company
InventorsJohn M. Domagala, John S. Kiely, Mel C. Schroeder
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Abstract
Individual stereoisomers of 7-[3-(1-aminoalkyl)-1-pyrrolidinyl]-quinolones and naphthyridones are described, their therapeutic advantages as antibacterial agents, as well as a novel method for the preparation and isolation of such stereoisomers.
Claims11
A 3S,1R stereoisomer of a compound of the formula ##STR18## wherein * denotes an asymmetric carbon atom;
- X is C-CF.sub.3 ;
- R.sub.1 is ethyl, cyclopropyl, or
- 2.
Dependencies are inferred from the claim text.